Top Selling Pharmaceuticals for 2003

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Sales Rank* Brand Name Trade Name Manufacturer Indication(s)** Rx Number*
1 Hydrocodone w/APAP Hydrocodone w/APAP Various pain 85,112,785
2 Lipitor Atorvastatin Pfizer US Pharm prevention of cardiovascular disease, hypercholesterolemia 65,529,814
3 Synthroid Levothyroxine Abbott hypothyroidism, euthyroid goiters 47,229,229
4 Atenolol Tenormin Various hypertension, angina pectoris, acute MI 40,919,771
5 Zithromax Azithromycin Pfizer US Pharm infections 39,535,047
6 Amoxil Amoxicillin Various infections 35,768,145
7 Furosemide Lasix Various edema, hypertension, acute pulmonary edema 35,093,279
8 Hydrodiuril Hydrochlorothiazide Various edema, hypertension 34,172,989
9 Norvasc Amlodipine besylate Pfizer US Pharm hypertension, coronary artery disease 33,331,079
10 Zestoretic Lisinopril Various hypertension, heart failure, acute MI 32,221,108
11 Xanax Alprazolam Various anxiety disorder, panic disorder 30,786,016
12 Zoloft Sertraline Pfizer US Pharm depression, OCD, panic disorder, PTSD, PMDD, social anxiety 29,664,731
13 Proventil Albuterol aerosol Various bronchospasm, asthma 29,228,793
14 Toprol-XL Metoprolol AstraZeneca hypertension, angina pectoris, heart failure 28,103,595
15 Zocor Simvastatin MSD reduction of CHD, hypercholesterolemia 27,420,730
16 Premarin Conjugated Estrogens Wyeth Pharm menopausal symptoms, breast cancer (palliation), prostate carcinoma, postmenopausal osteoporosis 26,269,932
17 Prevacid Lansoprazole Tap Pharm duodenal and gastric ulcer, GERD, erosive esophagitis, Zollinger-Ellison syndrome 25,582,478
18 Zyrtec Cetirizine Pfizer US Pharm allergic rhinitis, chronic urticaria 24,255,493
19 Motrin Ibuprofen Various rheumatoid arth, osteoarth, pain, primary dysmenorrhea 23,558,526
20 Levoxyl Levothyroxine Monarch Pharm hypothyroidism, pituitary TSH suppression 22,434,667
21 Darvon Propoxyphene Various pain 22,093,413
22 Dyrenium Triamterene Various edema 21,973,247
23 Celebrex Celecoxib Pharmacia Upjohn osteoarth, rheumatoid arth, familial adenomatous polyposis 21,771,300
24 Ambien Zolpidem Sanofi insomnia 21,457,104
25 Allegra Fexofenadine Aventis allergic rhinitis, chronic idiopathic urticaria 21,205,541
26 Keflex Cephalexin Various infections 21,075,715
27 Nexium Esomeprazole AstraZeneca GERD, gastric ulcer 21,028,143
28 Fosamax Alendronate MSD osteoporosis 20,580,963
29 Vioxx
(not in US since '04)		 Rofecoxib MSD osteoarth, rheumatoid arth, pain, juvenile rheumatoid arth, acute pain, primary dysmenorrhea, migrane 18,938,103
30 Singulair Montelukast MSD asthma, allergic rhinitis 18,519,726
31 Ortho Tri-Cyclen Norgestimate/Ethinyl Estradiol Ortho -- 18,479,661
32 Deltasone Prednisone Various endocrine disorders, rheumatic disorders, collagen diseases, dermatological diseases, allergies, ophthalmic diseases, respiratory diseases, hematologic disorders, neoplastic diseases, edematous states, GI diseases, nervous system, misc 18,384,356
33 Lopressor Metoprolol tartrate Various hypertension, angina pectoris, MI 17,252,205
34 Prozac Fluoxetine Various depression, OCD, bulimia nervosa, panic disorder 17,136,837
35 Effexor XR Venlafaxine hydrochlorids Wyeth Pharm depression, genl anxiety disorder, social anxiety disorder 17,059,254
36 Neurontin Gabapentin Pfizer US Pharm postherpetic neuralgia, epilepsy 16,896,050
37 Ativan Lorazepam Various anxiety 16,031,957
38 Klonopin Clonazepam Various seizure disorders, panic disorder 16,004,921
39 Celexa Citalopram Forest depression 15,965,999
40 Viagra Sildenafil Citrate Pfizer US Pharm erectile dysfunction 15,917,117
41 Zyban/Wellbutrin bupropion HCL GlaxoSmithKline ------- 15,614,591
42 Paxil Paroxetine GlaxoSmithKline ---------- 15,613,429
43 Pravachol Pravastatin BMS Primary Care ---------- 15,309,178
44 Plavix Clopidogrel BMS Primary Care   15,175,822
45 Trimox Amoxicillin Sandoz infection 15,103,044
46 Potassium Chloride Potassium Chloride Various   14,975,013
47 Protonix Pantoprazole Wyeth Pharm   14,956,685
48 Advair Diskus Salmeterol/Fluticasone GlaxoSmithKline   14,896,462
49 Flonase Fluticasone Allen&Hanburys   14,549,702
50 Metformin Metformin Various diabetes 14,201,553
51 Amoxicillin/Clavulanate Amoxicillin/Clavulanate Various   14,194,827
52 Amitriptyline Amitriptyline Various   13,744,514
53 Ranitidine HCl Ranitidine Various   13,705,061
54 Acetaminophen/Codeine Acetaminophen/Codeine Various   13,565,004
55 Lexapro Escitalopram Forest Pharm   13,532,871
56 Accupril Quinapril Pfizer US Pharm   12,770,149
57 Levaquin Levofloxacin Ortho infection 12,642,583
58 Altace Ramipril Monarch Pharm   12,057,226
59 Diovan Valsartan Novartis   11,654,378
60 Lotrel Amlodipine / Benazepril Novartis   11,426,715
61 Warfarin Warfarin Barr   11,260,847
62 Omeprazole Omeprazole Kremers Urban   10,937,547
63 Cyclobenzaprine Cyclobenzaprine Various   10,783,876
64 Glucotrol XL Glipizide Pfizer US Pharm   10,747,451
65 Diflucan Fluconazole Pfizer US Pharm   10,733,924
66 Verapamil Verapamil Various   10,467,787
67 Bextra Valdecoxib Pharmacia Upjohn pain 9,931,475
68 Penicillin VK Penicillin VK Various infection 9,724,240
69 Cozaar Losartan MSD   9,480,722
70 Actos Pioglitazone Takeda   9,328,213
71 Trazodone Trazodone Various   9,275,431
72 Glyburide Glyburide Various   9,233,740
73 Naproxen Naproxen Various pain 9,122,527
74 Diovan HCT Valsartan / HCTZ Novartis   8,906,553
75 Coumadin Warfarin BMS   8,870,309
76 Ortho Evra Norelgestromin / Ethinyl Estradiol Ortho   8,849,433
77 Avandia Rosiglitazone maleate GlaxoSmithKline   8,839,011
78 Paxil CR Paroxetine GlaxoSmithKline   8,580,523
79 Risperdal Risperidone Janssen   8,101,705
80 Flomax Tamsulosin Abbott   8,096,008
81 Aciphex Rabeprazole Eisai   8,070,778
82 Digitek Digoxin Bertek   7,997,516
83 Cipro Ciprofloxacin Bayer infection 7,983,181
84 Nasonex Mometasone Schering   7,969,224
85 Oxycodone/APAP Oxycodone/APAP Mallinkrt Pharm pain 7,734,915
86 Glucophage XR Metformin BMS Primary Care   7,696,954
87 Lotensin Benazepril Novartis   7,629,962
88 Evista Raloxifene Lilly   7,612,336
89 Zyprexa Olanzapine Lilly   7,512,062
90 Diltiazem HCl Diltiazem Various   7,322,514
91 Allegra-D Fexofenadine / Pseudoephedrine Aventis allergy 7,284,963
92 Clonidine Clonidine Mylan   7,246,826
93 Lanoxin Digoxin GlaxoSmithKline   7,140,081
94 Hyzaar Losartan/HCTZ MSD   7,137,316
95 Amoxil Amoxicillin GlaxoSmithKline   7,060,402
96 Actonel Risedronate P&G Pharm   7,017,093
97 Oxycontin Oxycodone Purdue pain 6,979,704
98 Cotrim Trimeth/Sulfameth Teva   6,892,585
99 Xalatan Latanoprost Pharmacia Upjohn   6,890,883
100 Tricor Fenofibrate Abbott   6,888,346
101 Amaryl Glimepiride Aventis   6,865,111
102 Concerta Methylphenidate XR McNeil   6,849,556
103 Flovent Fluticasone Propionate GlaxoSmithKline   6,719,027
104 Glucovance Glyburide / Metformin BMS Primary Care   6,703,701
105 Combivent Ipratropium / Albuterol BI   6,690,799
106 Adderall XR Amphetamine Mixed Salts Shire   6,317,717
107 Prilosec Omeprazole AstraZeneca   6,136,591
108 Seroquel Quetiapine AstraZeneca   6,106,477
109 Yasmin 28 Drospirenone / Ethinyl Estradiol Berlex   6,004,830
110 Valtrex Valacyclovir GlaxoSmithKline   5,877,277
111 Depakote Divalproex Abbott   5,769,567
112 Prempro Conj. Estrogens/Medroxyprogesterone Wyeth   5,757,472
113 Carisoprodol Carisoprodol Various   5,748,228
114 Isosorbide Mononitrate Isosorbide Mononitrate S.A. Warrick   5,664,273
115 Levothroid Levothyroxine Forest Pharm   5,481,429
116 Avapro Irbesartan BMS Primary Care   5,391,251
117 Diazepam Diazepam Mylan   5,358,380
118 Detrol LA Tolterodine Pharmacia Upjohn   5,271,359
119 Humulin N Human Insulin NPH Lilly diabetes 5,260,085
120 Lantus Insulin Glargine Aventis   5,216,039
121 Coreg Carvedilol GlaxoSmithKline   5,180,012
122 Enalapril Enalapril Various   5,124,866
123 Ultracet Tramadol / Acetaminophen McNeil   5,066,385
124 Promethazine Promethazine Sandoz   5,037,919
125 Endocet Oxycodone/APAP Endo   5,029,495
126 Gemfibrozil Gemfibrozil Teva   5,002,646
127 Topamax Topiramate McNeil   4,966,738
128 Skelaxin Metaxalone Monarch Pharm pain 4,957,509
129 Biaxin XL Clarithromycin Abbott infection 4,848,527
130 Cartia XT Diltiazem Andrx   4,776,445
131 Monopril Fosinopril BMS Primary Care   4,771,618
132 Zetia Ezetimibe Merck / Schering   4,768,679
133 Folic Acid Folic Acid Danbury   4,727,111
134 Rhinocort Aqua Budesonide AstraZeneca   4,712,717
135 Omnicef Cefdinir Abbott   4,699,656
136 Meclizine Meclizine Par Pharm   4,683,529
137 Nasacort AQ Triamcinolone Acetonide Aventis   4,626,260
138 Augmentin ES-600 Amoxicillin/Clavulanate GlaxoSmithKline   4,583,814
139 Macrobid Nitrofurantoin P&G Pharm   4,576,805
140 Temazepam Temazepam Mylan   4,523,113
141 Doxycycline Hyclate Doxycycline Watson   4,489,152
142 Imitrex Sumatriptan GlaxoSmithKline   4,469,242
143 Necon Ethinyl Estradiol / Norethindrone Watson   4,396,480
144 Klor-Con Potassium Chloride Upsher-Smith   4,391,741
145 Klor-Con M20 Potassium Chloride Upsher-Smith   4,297,643
146 Allopurinol Allopurinol Mylan   4,295,383
147 Dilantin Phenytoin Pfizer Pharm   4,204,117
148 SMZ-TMP Trimeth/Sulfameth Mutual   4,175,724
149 Microgestin Fe Norethindrone/Ethinyl Estradiol Watson   4,089,769
150 Humalog Insulin Lispro Lilly   4,085,861
151 Cefzil Cefprozil BMS Primary Care   4,022,708
152 Duragesic Fentanyl Janssen pain 3,914,643
153 Bactroban Mupirocin GlaxoSmithKline   3,897,112
154 Patanol Olopatadine Alcon   3,882,259
155 Humulin 70/30 Human Insulin 70/30 Lilly   3,875,494
156 Aricept Donepezil Eisai   3,777,051
157 Miralax PEG 3350 Braintree   3,744,671
158 Aviane Levonorgestrel/Ethinyl Estradiol Barr   3,693,124
159 Zyrtec-D Cetirizine / Pseudoephedrine Pfizer US Pharm   3,627,955
160 Ditropan XL Oxybutynin McNeil   3,624,072
161 Biaxin Clarithromycin Abbott   3,584,713
162 Ciprofloxacin Ciprofloxacin Barr   3,582,316
163 Niaspan Niacin Koss Pharm   3,559,888
164 Strattera Atomoxetine Lilly   3,421,441
165 Inderal LA Propranolol Wyeth Pharm   3,399,036
166 Elidel Pimecrolimus Novartis   3,336,954
167 Pulmicort Budesonide AstraZeneca   3,334,585
168 Trivora-28 Levonorgestrel / Ethinyl Estradiol Watson   3,234,190
169 Albuterol Albuterol Warrick   3,233,154
170 Nifedipine ER Nifedipine Barr   3,221,416
171 Methylprednisolone Methylprednisolone Barr   3,179,121
172 Tussionex Hydrocodone / Chlorpheniramine Celltech Pharm   3,152,021
173 Mobic Meloxicam Abbott pain 3,136,561
174 Timolol Timolol Falcon Pharm   3,099,463
175 Atacand Candesartan AstraZeneca   3,079,027
176 Phenytoin Phenytoin Mylan   3,047,807
177 Alphagan P Brimonidine Allergan   3,046,454
178 Avelox Moxifloxacin Bayer   3,042,473
179 Clotrimazole / Betamethasone Clotrimazole / Betamethasone Taro Pharm USA   2,940,668
180 Triamcinolone Triamcinolone Fougera   2,922,925
181 Lescol XL Fluvastatin Novartis   2,920,242
182 Miacalcin Calcitonin Novartis   2,899,001
183 Ortho-Novum Norethindrone/Ethinyl Estradiol Ortho-McNeil   2,895,989
184 Plendil Felodipine AstraZeneca   2,892,038
185 Promethazine/Codeine Promethazine / Codeine Alpharma US   2,879,737
186 Nitroquick Nitroglycerin Ethex   2,877,665
187 Spironolactone Spironolactone Mylan   2,851,944
188 Terazosin Terazosin Sandoz   2,850,465
189 Proscar Finasteride MSD   2,838,126
190 Avalide Irbesartan / HCTZ BMS Primarycare   2,816,202
191 Kariva Desogestrel / Ethinyl Estradiol Barr   2,800,150
192 Low-Ogestrel Norgestrel / Ethinyl Estradiol Watson   2,777,908
193 Tobradex Tobramycin / Dexamethasone Alcon   2,772,278
194 Remeron Mirtazapine Organon   2,749,113
195 Roxicet Oxycodone / Acetaminophen Roxane pain 2,748,863
196 Percocet Oxycodone / Acetaminophen Endo pain 2,716,701
197 Atrovent Ipratropium BI asthma, bronchitis, emphysema 2,689,362
198 Propranolol Propranolol Pliva hypertension, angina, etc 2,685,670
199 Nifediac CC Nifedipine Teva hypertension 2,670,163
200 Apri Desogestrel/Ethinyl Estradiol Barr contraception 2,667,824

* data from: Physician's Desk Reference
** data from: RxList
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Peter A. Ensminger, ensmingr (at) twcny (dot) rr (dot) com
updated: March 15, 2007
 
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